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cibior D, Czeczot H

In addition to the rapid epigenetic modulation of glutamatergic function, preclinical studies showed that boosting mitochondrial metabolism of LAC protects against oxidative stress, rapidly ameliorates insulin resistance, and reduces neuroinflammation by decreasing proinflammatory pathways such as NFkB in hippocampal and cortical neurons

Culture of these cells with the alcohol soluble fraction of Protandim (20 g/ml) for 6 h resulted in the appearance of Cy3 signal mostly in the nucleus